ISAAC is a highly interdisciplinary research institute supporting the energy system transition towards sustainability. Its main focus is on the decentralized energy generation with photovoltaics, the decarbonization of mobility and buildings through innovative and active building skins, the digitization of energy in the innovative demand side management approaches, and the understanding of social and behavioural changes in living labs and smart cities. The institute’s activities embrace applied research, consulting and teaching to transfer to the young generation and local professionals the latest know-how.